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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related macular degeneration (AMD)
ncRNA name NF-κB p65 siRNA
ncRNA Category siRNA
Disease name age-related macular degeneration (AMD)
Species Homo sapiens
Tissues/Cell_line human RPE cell line ARPE-19
Methods RT-PCR, qRT-PCR, ELISA, siRNA transfection, luciferase reporter assay, Western blot
Expression pattern associated
Functional description KnockDown of NF-κB p65 decreased TG-Induced IL-8 rxpression in ARPE-19 cells.
PubMed ID 25593029
Year 2015
Title Involvement of intracellular calcium mobilization in IL-8 activation in human retinal pigment epithelial cells.
Drug-related ncRNA NO

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